To analyze the effects of ginkgo combined with edaravone on neurological function and stress index for the patients with acute cerebral infarction. Methods:From April 2016 to April 2017, a total of 112 patients with acute cerebral infarction in Chaoyang Central Hospital were selected. According to the different scheme, they were divided into two groups. The control group (n=54) was treated with edaravone and the observation group (n=58) was given ginkgo combined with edaravone. The neurotransmitter index, stress index and NIHSS score of nerve function were detected for 1 day before treatment and 14 days after treatment. The effects were compared between two groups. Results:1) In the observation group after the treatment, AOPP (75.12±3.74) μmol/L, IL-6 (71.62±5.01) pg/mL, ox-LDL (85.80±5.26) U/mL, CRP (9.18±0.55) mg/L, MDA (3.08±0.56) nmol/mL, IL-10 (22.13±1.62) μg/L were significantly lower than those in the control group. GSH-Px (39.18±6.28) mg/mL, SOD (162.54±13.15) U/mL were significantly higher than that in the control group (P<0.05). 2) In the observation group after the treatment, VAP (8.12±1.74) ng/L, NPY (170.52±6.15) μg/L, NSE (12.13±1.62) μg/L, Glu (71.62±4.01) μmol/L were significant lower than those in the control group. NGF (89.18±3.28) pg/mL, GABA (9.08±0.86) μmol/L, NTF (5.80±0.76) ng/mL, NAA (429.18±17.55) mmol/L were significant higher than those in the control group (P<0.05). 3) In the observation group after the treatment, the total NIHSS score (11.50±1.62) was significantly lower than that in the control group (18.00±1.78) (P<0.05). 4) The total effective rate in the observation group was 96.55%. It was significantly higher than that in the control group (87.04%) (P<0.05). Conclusion:For the treatment of acute cerebral infarction, ginkgo can effectively regulate the stress response, neurotransmitter expression and improve the neurological function of the patients compared with edaravone alone.