Abstract:To explore the effects of Jintiange Capsules on the expression of inflammatory factors in patients with osteoporotic fracture.Methods:A total of 140 cases of patients with osteoporotic fracture admitted to Yan'an Hospital of Kunming City from January 2016 to December 2016 were included and were divided into study group and control group according to the joining order,with 70 cases in each group.The control group was given oral calcium element tablets of Caltrate,while the study group was given Jintiange Capsules orally for 6 months.Results:The levels of TNF-α,IL-1,IL-6,IL-10,IL-17 and MCP-1 of the study group were significantly lower than those of the control group after 3 months of treatment.The levels of TNF-Α,IL-1,IL-10,IL-17 and MCP-1 of the study group were significantly lower than those of the control group after 6 months of treatment (P<0.05).The levels of L1-4 BMD of the study group was significantly higher than that of the control group at the same period (P<0.05).The level of L1-4 BMD in patients with osteoporosis showed a significant negative correlation with TNF-α,IL-1,IL-10,IL-17 and MCP-1 (P<0.05).Conclusion:Jintiange Capsules can effectively improve the bone mineral density of L1-4 bone in patients with osteoporotic fracture,and one of the mechanisms may be its effects in suppressing the expression of inflammatory factors of bone cells.