Skeletal muscle injury is one of the common clinical injury diseases and often causes serious adverse consequences to the injured. In recent years，many experiments and studies have confirmed that growth factor is one of the important factors affecting the repair of skeletal muscle injury. Massage，as one of the most commonly used and effective treatment methods for clinical skeletal muscle injury，plays an extremely important role in the treatment of skeletal muscle injury. Related experiments and studies have proved that the mechanism of massage in treating skeletal muscle injury is related to the intervention on the related growth factors.