To investigate the inhibitory effects of Qingguang'an Granule on filtering bleb scar after glaucoma filtration. Methods:A total of 76 patients with filtering bleb scar after glaucoma filtration in the First Hospital of Hunan University of Chinese Medicine from April 2016 to September 2018 were selected and divided into the observation group and the control group according to the random number table method，with 38 cases in each group. The 2 groups were treated with conventional trabeculectomy and filtration. The control group was given Xueshuantong Capsule after operation，while the observation group was given Qingguang'an Granules. The 2 groups were treated continuously for 2 months. The success rate of the 2 groups，the best corrected visual acuity(BCVA)and intraocular pressure at different times before and after operation were compared. The postoperative complications of the 2 groups were recorded. Results:Functional blebs were formed in the eyes of the 2 groups at 7 days after operation. The treatment success rate of the observation group was significantly higher than that of the control group(P<0.05). Compared with preoperative situation，the BCVA and filtering bleb height significantly increased in the 2 groups at 1 and 2 months after operation. The observation group was significantly higher than that of the control group(P<0.05). The intraocular pressure significantly decreased，of which the experiment group was significantly lower than that of the control group(P<0.05). There was no significant difference in the incidence of total complications between the 2 groups(P>0.05). Conclusion:The application of Qingguang'an Granules after glaucoma filtration can significantly increase BCVA，reduce intraocular pressure as well as effectively inhibit bleb scarring.