To analyze the migration of elements in Thrombus Scavenger Injection from material to product，and to control the elemental impurities in products.Methods:The quantities of 21 elements in Panax notoginseng，Panax noteginseng saponins and Thrombus Scavenger Injection were determined by ICP-MS.Results:The correlative coefficients of standard curves of 21 elements surpassed 0.999，with the average recoveries ranged from 92.71% to 107.07% and their RSDs within 5%.The quantities of Al and Fe in Panax notoginseng were higher，while Pb，As，Hg，Cd，Cu was less than the standards of Chinese Pharmacopoeia.Most elements in Panax noteginseng saponins and Thrombus Scavenger Injection were not detected or were extremely low.Conclusion:The quantities of the heavy metal and hazard elements and other elements in Panax notoginseng were greatly reduced by the extraction process of Thrombus Scavenger Injection.