To explore the clinical efficacy of Chinese medicine fumigation combined with artificial tear in the treatment of dry eye，and analyze the effects on the vision-related life quality.Methods:A total of 72 cases patients with dry eye treated in Beijing Jiangong Hospital from November 2014 to December 2016 were divided randomly into the control group(n＝36，72 cases eyes）and the observation group(n＝36，72 cases eyes）according to random number table.The control group was treated with artificial tear，and the observation group was treated with Chinese medicine fumigation on the basis of control group，2 weeks as 1 course，and 2 groups were treated for 2 courses.The clinical efficacy of 2 groups were statisticsed; the main Chinese medicine symptom integrals of 2 groups before and after treatment were evaluated and compared; the lacrimal secretion and breakup time of tear film in 2 groups before and after treatment were detected and compared; the vision-related life quality of 2 groups before and after treatment were evaluated and compared by the U.S.national eye institute visual related quality of life scale-25(NEI-VFQ-25).Results:The total effective rate of study group was 90.28%，which was higher than that 63.89% of control group(P<0.01); Compared with before treatment，the symptoms integrals of fatigue feeling，dry feeling，foreign body sensation and burning sensation decreased significantly，and the observation group was lower than control group; Compared with before treatment，the lacrimal secretion showed a trend of increasing gradually from 2 to 4 weeks after treatment(P<0.01)，and the breakup time of tear film showed a trend of decreasing gradually(P<0.05)，and the difference between the 2 groups after treatment was significant(P<0.05 or P<0.01); Compared with before treatment，the scores of general health，movement disorder and visual impairment of eyes in 2 groups after treatment increased significantly(P<0.01)，and the observation group was higher than control group(P<0.01).Conclusion:Chinese medicine fumigation combined with artificial tear can remit the clinical syndromes of patients with dry eye，promote the tear secretion and enhance the tear film stability effectively，and which can improve the vision-related life quality of eyes.The clinical efficacy is better than artificial tear alone.