To investigate the clinical effects of Compound Danshen Dripping Pills combined with laser photocoagulation on diabetic retinopathy.Methods:A total of 80 patients with type 2 diabetic retinopathy admitted in the 940th Hospital of Joint Logistics Support force of Chinese People's Liberation Army from January 2014 to January 2016 were included as the research object，randomly divided into the treatment group(n＝43）and the control group(n＝37).All patients had received hypoglycemic，hypotensive and other internal medicine treatments before the study.The treatment group was treated with Compound Danshen Dripping Pills combined with laser photocoagulation，while the control group only received laser photocoagulation treatment.The changes in visual acuity，hemangioma，macular thickness and threshold sensitivity within 30 degrees in two groups of patients before and after treatment; tested the changes in the levels of vascular endothelial growth factor(VEGF)，interleukin 1β(IL-1β)，vascular endothelial cell adhesion 1(VCAM-1）and nuclear factor kappa B(NF-κB）were observed by enzyme-linked immune sorbent assay(ELISA).Results:After the treatment，the visual acuity，hemangioma，macular thickness，threshold sensitivity within 30 degrees of patients of the treatment group were significantly improved; the serum levels of VEGF，IL-1，VCAM-1 and NF-β Kappa B of patients in the treatment group were lower than those of the control group(P<0.05)，whose difference was statistically significant.Conclusion:Compound Danshen Dripping Pills combined with laser photocoagulation can effectively improve the ischemia and hypoxia condition of the retinal tissue，as well as the threshold sensitivity within 30 degrees and the macular thickness，improve，and life quality of patients.