Chronic kidney disease is currently a global public health problem,but the clinical manifestations and signs of chronic kidney disease are few in the early stages,and it is easy to be neglected.If it is not treated in the early and middle stages,it will soon progress to end-stage renal disease(ESRD).The author organized and summarized the clinical ideas and experiences of Professor He Liqun in the treatment of chronic kidney disease with traditional Chinese medicine,and attaching one case,sharing it with you.