To study the therapeutic effects of Xiaoer Yanbian Granules on acute pharyngitis according to its clinical indications.Methods:Acute pharyngitis in rats was induced by pharyngeal ammonia spray to observe the effects of Xiaoer Yanbian Granules on the immune function and serum inflammatory factors,and the protective effect in pharynx mucosa.Results:After 7 days of continuous administration,there was a significant difference in the apparent index score between the model group and the normal group(P<0.05).The low dose of Xiaoer Yanbian Granules significantly reduced the apparent index score.After 7 days of continuous administration,the pathological results showed that the low,medium and high doses of Xiaoer Yanbian Granules could improve the pharyngeal inflammation to different degrees.The results of serum inflammatory factor test showed that the concentration of serum inflammatory factor TNF-α was decreased to different degrees in different dosage groups of Xiaoer Yanbian Granules(P<0.05; P<0.01).Conclusion:Xiaoer Yanbian Granules could improve immune function,reduce serum inflammatory factors of rats with acute pharyngitis and protect the pharynx mucosa to some extent.