Abstract:To explore the efficacy of Huoxue Tongluo Qingnao Powder combined with ozagrel sodium on neurological function in elderly patients with transient ischemic attack (TIA).Methods:A total of/Totally 124 cases of elderly TIA patients in Haian Hospital Affiliated to Nantong University from August 2016 to December 2017 were selected and randomly divided into the observation group and the control group,with 62 cases in each group.The 2 groups received routine symptomatic treatment,while the control group was given ozagrel sodium on the basis of conventional treatment.The observation group was additionally given Huoxue Tongluo Qingnao Powder on the basis of the control group.The 2 groups were treated with 10 d for 1 treatment cycle,and the clinical efficacy was observed after 2 cycles of treatment.The patients in the 2 groups were followed-up regularly for 6 months.The clinical efficacy of the 2 groups was compared,and the changes of nerve function and platelet activation function indexes of the 2 groups were detected and compared.The prognosis of patients in 2 groups was compared during the follow-up period.Results:The total effective rate of the observation group and the control group were 75.81% and 56.45% respectively after treatment,and the total effective rate of the observation group was significantly higher than that of the control group (P<0.05).The scores of vertigo symptoms and symptoms of apoplexy aura of the 2 groups after treatment were lower than before treatment (P<0.01),and the observation group was lower than the control group (P<0.01).The levels of NSE,S-100B,GFAP,platelet aggregation,GMP-140 and PAF of the 2 groups after treatment were lower than those before treatment (P<0.05 or P<0.01),and the observation group was lower than that of the control group (P<0.01).The NHISS scores of the 2 groups after treatment were lower than that before treatment,and the Barthel score was higher than that before treatment,and there was a significant difference between the 2 groups (P<0.01).The incidence of recurrent and focal neurological deficits in the observation group was significantly lower than that of the control group (P<0.05),but there was no significant difference in the incidence of cardiovascular events between the 2 groups (P>0.05).Conclusion:Huoxue Tongluo Qingnao Powder combined with ozagrel sodium is effective in the treatment of elderly TIA patients.It can improve platelet activity and nerve function,and the clinical recurrence rate and the incidence of focal neurological deficit are lower.It is worthy of clinical popularization.