Abstract:To explore the effects of astragalus injection combined with taurine on immune function of acute viral myocarditis (AVMC) patients.Methods:A total of 135 cases AVMC patients admitted to Fuwai Central China Cardiovascular Hospital from April 2014 to May 2017 were selected and divided into a control group (n=67) and an observation group (n=68) according to random number table method.The control group received conventional treatment+taurine treatment,and the observation group was treated with astragalus injection on the basis of the control group.Both groups were all treated continuously for 4 weeks.The clinical curative effect,traditional Chinese medicine syndrome scores and total scores in the 2 groups were calculated after treatment; the myocardial enzyme spectrum,serum inflammatory cytokines and cellular immunity index in the 2 groups were measured before and after treatment.Results:The total clinical efficiency in the observation group after treatment was 92.65%,which was significantly higher than that 68.66% in control group (P<0.01); compared with before treatment,the palpitations,chest tightness,limb cold and sweating,dizziness,shortness of breath and weakness scores and total scores in the 2 groups decreased significantly after treatment (P<0.01),and the observation group was significantly lower than the control group (P<0.05 or P<0.01); compared with before treatment,the serum LDH,CK,CK-MB,cTnI levels,and IL-6,TNF-α,hs-CRP levels in the 2 groups decreased significantly after treatment (P<0.01),and the observation group was significantly lower than the control group (P<0.01); compared with before treatment,the proportion of whole blood CD3+,CD4+,NK in the 2 groups and CD4+/CD8+ in the observation group increased significantly after treatment (P<0.01),and the observation group was significantly higher than the control group (P<0.01); there was no significant difference in the proportion of whole blood CD8+ between before and after treatment as well as the 2 groups after treatment.The CD4+/CD8+ of control group had no difference compared with before treatment (P>0.05).Conclusion:Astragalus injection combined with taurine can significantly alleviate the clinical symptoms of AVMC patients,reduce the inflammatory response,enhance their immune function and improve myocardial function,and the efficacy is significantly better than taurine treatment alone.