To investigate the clinical effects of small needle knife combined with Juanbi Decoction on knee osteoarthritis of liver and kidney deficiency type.Methods:A total of 126 patients with osteoarthritis of knee joint of liver and kidney deficiency type admitted to Shunyi Hospital of Beijing Hospital of Traditional Chinese Medicine from May 2017 to January 2019 were selected and divided into an observation group and a control group according to random number table method,with 63 cases in each group.The control group was treated with small needle knife alone,while the observation group was treated with Juanbi Decoction on the basis of the control group.The clinical efficacy,knee joint function score (HSS score),joint swelling score,bony crepitus and TCM syndrome score of 2 groups were observed before and after treatment.Results:The total effective rate of the observation group was 95.2% (60/63),higher than that of the control group 82.5% (52/63),and there was significant difference (P<0.05); before treatment,there was no significant difference in HSS score,joint swelling score,bony crepitus and TCM syndrome score between the 2 groups (P>0.05); after treatment,the pain score,function score and total score of the observation group were higher than those of the control group (P<0.05).The score of joint swelling,the number of joints with bony crepitus and the score of TCM syndromes in the observation group were lower than the control group (P<0.05).Conclusion:Small needle knife combined with Juanbi Decoction is effective in treating knee osteoarthritis of liver and kidney deficiency type.It can effectively relieve inertia pain,improve knee function and reduce the degree of joint swelling.It is worthy of clinical application.