Modern medicine shows that the umbilical cord is the last closed part of the abdominal wall during the embryonic development,and its epidermal cuticle is the thinnest with strong permeability,which is especially favorable for drug absorption.In traditional Chinese medicine,the umbilical cord is also called Shenque(RN8),which is the main treatment for all kinds of diseases.It can clear the whole body and stimulate the Shenjue(RN8）to regulate the whole body,thus achieving the effects of treating diseases.This paper reviewed the history,dosage form,drug use,and modern clinical application of umbilical cord administration in order to better use the advantages of this method in clinical practice.It also provides a reference for the further research and development of the application of volatile oil related preparations to umbilical therapy.