To compare the fingerprint difference of Buyang Huanwu Decoction between traditional decoction and modern decoction machine by high performance liquid chromatography(HPLC).Methods：Firstly，random number table method was used to randomly select the prescription of 10 different batches of Buyang Huanwu Decoction of different batches，prepared the traditional decoction of Buyang Huanwu Decoction，and the modern decocting machine Buyang Huanwu Decoction.After the optimized chromatographic conditions，the HPLC fingerprint was compared.Results：1)HPLC chromatography was used to make a specific test of Buyang Huanwu Decoction，the results showed that the Buyang Huanwu decoction had good specificity.2)The linear relationship showed the regression equation of ferulic acid y=259.33X+48.708，r=0.999 9(n=5).The results showed that the range of ferulic acid control was in 0.997～9.97 μg/μL，and the linear investigation showed that the linear relationship was good.3)The results of the precision test were 5% of the total peak area of the peak area of 5%，the average value of the relative peak area of the peak area was 2.014%，and the relative retention time of the chromatographic peak was 0.29% of the average value of RSD.The results showed that the precision of the solution of Buyang Huanwu decoction was good.4)Finally，the results of the stability test were 5% of the total peak area and the RSD average 1.839%.The chromatographic peak relative retention time RSD average value was 0.02%，and the research results showed that Buyang Huanwu decoction solution 24 h stability.5)The results of repeatability test were 5% of the total peak area，and the average value of the peak area was 1.901%，and the relative retention time of the chromatographic peak was 0.72%.The results of this study showed that the repeatability of Buyang Huanwu decoction was good.6)The average recovery was 99.76% and RSD was 2.14%.The results showed that the HPLC method under this chromatographic condition was reliable.7)The test results showed that the traditional decoction of Buyang Huanwu decoction fingerprint 131.88 min was completed，while the Buyang Huanwu decoction fingerprint made by the modern decocting machine was detected in 140 min，and the chromatogram peak of Buyang Huanwu decoction prepared by the modern decocting mechanism could be seen from the atlas.The average similarity of the traditional decocting method was 0.956 and the average similarity of the modern decocting machine method was 0.974，which is slightly higher than the traditional decocting method.Conclusion：The HPLC fingerprint of Buyang Huanwu decoction prepared by traditional decocting method and modern decocting machine is different.