To investigate the clinical effect of Xingnaojing combined with mouse nerve growth factor(NGF)in the emergency stage of cerebral hemorrhage.Methods：A total of 100 patients with cerebral hemorrhage were randomly divided into four groups，with 25 patients in each group，which were conventional treatment group，NGF group，Xingnaojing group and combined group; The conventional treatment group was given the treatment of citicoline sodium injection; NGF group on the basis of the conventional treatment group was injected NGF by muscle，once a day.Xingnaojing group were given Xingnaojing on the basis of the conventional treatment group by intravenous drip，once a day.The usage and dosage of combined group was consistent with the above three groups; All patients were treated for 2 weeks.After treatment，the clinical efficacy of patients was evaluated according to NIHSS score.Changes in serum neuron-specific enolase(NSE)and homocysteine(Hcy)before and after treatment were compared，and changes in cerebral edema volume of patients with cerebral hemorrhage were recorded.Results：NGF group，Xingnaojing group and combined group of NIHSS score were lower than the conventional treatment group after treatment，which the lowest score.Combined group compared with the conventional treatment group had statistically significant difference(P<0.05); the markedly efficiency of NGF group，Xingnaojing group and combined group were higher than conventional treatment group(56%)，among which the combined group efficiency was up to 88%，which was statistically significant compared with the conventional treatment group(P<0.05); After treatment，serum NSE and Hcy concentrations of patients in the four groups decreased significantly compared with those before treatment，with the lowest decrease in the combined group(NSE=18.51±3.28 g/mL，Hcy=9.55±2.44 mol/L).NGF group and xingnaojing group had similar NSE and Hcy concentration.After treatment，the volume of cerebral edema in NGF group，xingnaojing group and combined group was significantly lower than that in conventional treatment group.There was no statistical significance before treatment in each group(P>0.05)，and there was statistical significance after treatment in each group(P<0.05).There was statistical significance before and after treatment in the same group(P<0.05)，and there was statistical significance between NGF group，xingnaojing group and combined group and conventional treatment group(P<0.05).Conclusion：Mouse nerve growth factor in combination with Xingnaojing for emergency period in cerebral hemorrhage，the clinical curative effect is distinct，being worthy of promotion.