To observe and analyze the effects of Shengyang Yishen decoction on the expression of immunoglobulin lgE，lgM，lgA and lymphocytes in patients with allergic rhinitis with deficiency of lung and kidney yang.Methods：From January 2017 to January 2018，150 cases of allergic rhinitis with deficiency of lung and kidney yang in Tongji Hospital Affiliated to Tongji Medical College，Huazhong University of Science and Technology were given a retrospective analysis.According to the difference of treatment methods，the patients were divided into two groups：an observation group(routine western medicine treatment combined Shengyangyishen decoction，n＝89)and a control group(routine western medicine treatment，n＝61).The improvement of immunoglobulin IgE，lgM，lgA and lymphocytes after treatment and improvement of VAS sign score and QLQ-C30 score were observed，and the therapeutic effect was compared.Results：In the observation group，the improvement of IgE，lgM，lgA and lymphocytes，VAS sign score and QLQ-C30 score were better than those in the control group.The difference was statistically significant(P<0.05).Conclusion：Shengyang Yishen decoction has a positive effect on the expression of immunoglobulin and lymphocytes in allergic patients with deficiency of lung and kidney yang，and can effectively improve the effective rate of clinical treatment.The VAS signs of allergic rhinitis with deficiency of lung and kidney yang can be effectively alleviated，and the prognosis of patients can be effectively improved.