To explore clinical efficacy of Qiming Granules combined with Bailing Capsules in early chronic kidney diseases(CKD)and its effects on microinflammatory state.Methods：A total of 100 patients with early CKD admitted in the Lishui Hospital,Zhongda Hospital Affiliated to Southeast University from January 2016 to December 2018 were selected as research objects,and they were randomly divided into control group and observation group,with 50 patients in each group.After the admission,both groups of patients were given routine treatment such as blood pressure control,electrolyte disturbance correction and acid-base balance maintenance.The observation group was additionally given Qiming Granules and Bailing Capsules.After the treatment,the clinical efficacy of the 2 groups was analyzed.Levels of renal function,inflammatory factors,blood lipid,cystatin-C(Cys-C)and β2-microglobulin(β2-MG)were compared between the 2 groups before and after the treatment.Results：After the treatment,the total clinical effective rate of the observation group was 84.00%,which was significantly higher than that of the control group(66.00%,P<0.05).The levels of blood urea nitrogen(BUN),urinary albumin excretion rate(UAE),serum creatinine(SCr),triglyceride(TG),total cholesterol(TC),low density lipoprotein-C(LDL-C),high sensitivity C-reactive protein(hs-CRP),tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),Cys-C,and β2-MG in the 2 groups were all decreased,and the above indicators in the observation group were significantly lower than those in the control group(P<0.05).Conclusion：On the basis of the routine treatment,Qiming Granules combined with Bailing Capsules in the treatment of early CKD can effectively regulate blood lipid level,inhibit microinflammatory reaction and improve renal function of patients.