To observe the clinical effects and cost-effectiveness ratio analysis of Yangxinshi tablet in treating angina pectoris of qi deficiency and blood stasis syndrome.Methods：A total of 90 patients with angina pectoris of qi deficiency and blood stasis syndrome in the First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine were randomly divided into an observation group(routine western medicine+Yangxinshi）and a control group(routine western medicine),with 45 cases in each group.The clinical efficacy,the number of angina attacks,the rate of re-visit hospitalization,the effect of electrocardiogram,the cost-effectiveness ratio,and adverse reactions between the 2 groups within 3 months were observed and compared.Results：After treatment,the total effective rate was 95.6% in the observation group and 82.2% in the control group,and the difference was statistically significant(P<0.05).The number of angina attacks and the rate of re-visit hospitalization in the observation group were lower than that in the control group.The improvement of electrocardiogram in the observation group was significantly better than the control group(P<0.05).The cost-effectiveness ratio was 196.28 yuan in the observation group and 804.24 yuan in the control group.The cost of the observation group was 607.96 yuan less than that of control group in the treatment effects.There was no difference in adverse reactions between the 2 groups.Conclusion：Compared with the control group,the observation group can significantly improve the clinical efficacy and ECG,reduce the incidence of angina pectoris and hospitalization rate after re-visit,and effectively reduce the cost of treatment,and no more obvious adverse reactions were observed.