To discuss the clinical efficacy of modified Sijunzi Decoction in treatment of chronic heart failure with qi deficiency and phlegm-stasis syndrome.Methods：A total of 120 patients with chronic heart failure of qi deficiency and phlegm-stasis syndrome were selected in the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from January 2017 to December 2017and were divided into an observation group and a control group according to the random number table method，with 60 cases in each group.The control group received Enalapril combined with metoprolol treatment，and the modified Sijunzi Decoction was added in the observation group.Changes in the indexes of ventricular function，traditional Chinese medicine syndrome score and 6 min walking test of the 2 groups were observed at baseline phase and after treatment.The clinical efficacy was evaluated.Results：The effective rate of the observation group was higher than the control group，and the difference was statistically significant(P<0.05); At baseline phase，there was no statistically significant difference in the indexes of ventricular function，traditional Chinese medicine syndrome score and 6 min walking test(P>0.05); After treatment，traditional Chinese medicine syndrome score，LVEDD and LVESD of the observation group was significantly lower than the control group.The 6 min walking test and LVEF of the observation group was higher than the control group，with statistically significant difference(P<0.05).Traditional Chinese medicine syndrome score，LVEDD and LVESD of the 2 groups after treatment was significantly lower than that baseline phase(P<0.05); 6 min walking test and LVEF of the 2 groups after treatment was significantly higher than that at baseline phase，with statistically significant difference(P<0.05).Conclusion：Modified Sijunzi Decoction for patients with chronic heart failure with qi deficiency and phlegm-stasis syndrome has a good effect of syndrome differentiation and treatment.