Abstract:To study the effects of nourishing kidney and soothing liver method on the clinical symptoms,signs and growth of secondary sexual symptoms in girls with idiopathic central precocious puberty(ICCP).Methods:A total of 88 ICCP girls admitted to Beijing Children's Hospital Affiliated to Capital Medical University from June 2015 to June 2017 were randomly divided into a control group(n=44)and an observation group(n=44).The control group was given Dabuyin Pill.The observation group was treated with nourishing kidney and soothing liver method on the basis of the control group.The clinical efficacy of the 2 groups after treatment was compared.The ovarian and uterine volume,bone age and sex hormone levels of the 2 groups before and after treatment were compared.Results:After treatment,the total effective rate of the observation group was 95.5%,which was significantly higher than 72.7% of the control group; after treatment,the levels of FSH,LH and E2 in the 2 groups were significantly decreased(P<0.01),and the observation group was significantly lower than the control group(P<0.01); after treatment,the ovarian and uterine volumes of the 2 groups were significantly reduced(P<0.01),and the observation group was significantly lower than the control group(P<0.01); after treatment,the bone age of the 2 groups was significantly reduced(P<0.01),and the observation group was significantly lower than that of the control group(P<0.01).Conclusion:The method of nourishing kidney and soothing liver method can significantly improve the clinical therapeutic effect of ICCP girls,reduce the level of serum sex hormones,reduce the volume of ovary,uterus and bone age changes in advance,and has high safety.