Professor Guo Xiazhen summarized the special physiological characteristics of female menstruation,banding and pregnancy and the pathogenesis of infertility by understanding the basic theory of Inner Canon of Yellow Emperor,referring to the knowledge of doctors of past dynasties on the seeds of regulating menstruation and promoting pregnancy,inheriting Professor Cheng Shide's academic thought and clinical experience.Aiming at the regulation of the reproductive axis of kidney-Tiangui-Chongren-Cytogonium,a set of therapeutic principles and methods for regulating menstruation and promoting pregnancy are proposed,which are based on regulating yin and yang,tonifying kidney and benefiting essence,enriching qi and nourishing blood,soothing liver and relieving depression,and promoting blood circulation and softening firmness,which achieved good clinical efficacy.