To investigate the therapeutic effect of Guiqi Huoxue Capsule combined with glucosamine sulfate in the treatment of cervical spondylosis.Methods:A total of 100 patients with cervical spondylosis admitted to Qinghai University Affiliated Hospital from June 2016 to June 2018 were randomly divided into a control group and an observation group,with 50 patients in each group.Patients in the control group were given oral glucosamine sulfate twice a day,500 mg each time,for one month.The observation group was given oral Guiqi Huoxue Capsule on the basis of the control group,3 times a day,one capsule at a time.Both groups were treated continuously for one month.The clinical efficacy was observed after treatment.X-ray was used to exam cervical spine radian changes before and after treatment.Transcranial doppler(TCD)was used to detect the changes of blood flow velocity in basilar artery(BA)and bilateral vertebral artery(LVA and RVA)before and after treatment were used to evaluate the therapeutic effect of 2 groups.Results:The total effective rate in the observation group was 96% and the ineffective rate was only 4%.The effective rate of the control group was 86%,and the ineffective rate was 14%.The effect of the observation group was significantly better than that of the control group,and the difference between the 2 groups had statistical significance(P<0.05).After treatment,the curvature of the cervical spine in the treatment group improved to(11.62±3.78)mm and the difference between the 2 groups was statistically significant(P<0.05).After treatment,the blood flow velocity of basilar artery and bilateral vertebral artery was improved in both groups,and there was significant difference between the 2 groups before and after treatment(P<0.05).The effect of the observation group was better than the control group and the difference has statistical significance(P<0.05).Conclusion:Guiqi Huoxue Capsule combined with glucosamine sulfate has a significant effect on cervical spondylosis which is suitable for promotion.