To explore the curative effect of Mahuang Decoction combined with mechanical ventilation on acute myocardial infarction complicated with acute pulmonary edema.Methods:A total of 60 patients with acute myocardial infarction and acute pulmonary edema were enrolled as research objects in the Jilin Traditional Chinese and Western Medicine Hospital from September 2017 to November 2018.They were randomly divided into control group(30 cases)and observation group(30 cases)according to the order of admition.Heart failure was corrected and mechanical ventilation was performed in both groups.The observation group was also given Mahuang Decoction by nasal feeding，administered 3 times a day，for 7 d.Changes of respiration(RR)，heart rate(HR)，systolic blood pressure(SBP)，diastolic blood pressure(DBP)，arterial partial oxygen pressure(PaO2)，arterial partial pressure of carbon dioxide(PaCO2)，serum brain natriuretic peptide(BNP)，C-reactive protein(CRP)，APACHE II score，blood oxygen saturation(SaO2)，blood flow velocity of each valve orifice，clinical symptoms and clinical efficacy before and after the treatment were observed and compared between the 2 groups.Results:1)After the treatment，the RR，HR，SBP，DBP，PaCO2，BNP，CRP and APACHE II scores in the 2 groups were significantly decreased，while the PaO2 and SaO2 were significantly increased(P<0.05).The PaO2 and SaO2 in the observation group were significantly higher than those in the control group，and the remaining indicators were significantly lower than those in the control group(P<0.05). 2)After the treatment，the scores of chest tightness，palpitation，pink frothy sputum，lung rales and the tongue with purple and dark color or ecchymosis in the 2 groups were significantly lower than those before the treatment(P<0.05).After the treatment，the scores of the above indexes in the observation group were significantly lower than those in the control group(P<0.05). 3)The blood flow velocities at mitral valve，tricuspid valve，aortic valve and pulmonary valve and the LVEF were significantly higher in the 2 groups after the treatment than those before the treatment(P<0.05).There was no significant difference in the above indexes between the observation group and the control group after the treatment(P>0.05). 4)The marked and total effective rates in the observation group were significantly higher than those in the control group(P<0.05).Conclusion:Mahuang Decoction combined with mechanical ventilation can improve the clinical symptoms of acute myocardial infarction complicated with acute pulmonary edema，improve arterial blood gas，stabilize vital signs，promote blood flow velocity，and improve the curative effect.