To explore the effects of Banxia Baishu Tianma Decoction combined with Xuefu Zhuyu Decoction on endothelial function in hypertensive patients.Methods:A total of 80 hypertensive patients admitted to Zhangye People's Hospital Affiliated to Hexi University from January 2015 to June 2017 were divided into a control group and an observation group with 40 patients in each group according to random number table method.The control group was given the routine western medicine treatment,and the observation group was treated with Banxia Baishu Tianma Decoction combined with Xuefu Zhuyu Decoction on the basis of the control group.The levels of vascular endothelial factor(NO and ET-1 level),the therapeutic effect,blood pressure and TCM syndrome score were observed and compared between the 2 groups after treatment.Results:After treatment,the total effective rate in the observation group was 92.50% and the total effective rate in control group was 72.50%.The difference between the 2 groups was statistically significant(P<0.05).The diastolic blood pressure and systolic blood pressure all decreased in both groups and the decline in the observation group was more obvious than those in the control group(P<0.05).The levels of NO of the 2 groups patients increased,while the levels of ET-1 all decreased,and the changes in the observation group were more significant than that in the control group(P<0.05).The TCM syndrome score all decreased in both groups and the decline in the observation group was more obvious than those in the control group(P<0.05).Conclusion:Banxia Baishu Tianma Decoction combined with Xuefu Zhuyu Decoction can significantly increase the level of NO and reduce the level of ET-1,effectively decrease the blood pressure in hypertensive patients,which has a good clinical effect and is worthy of promotion and application.