To study application efficacy of Pingchuan Zhike Decoction in patients with chronic obstructive pulmonary disease(COPD）during acute episode and its effects on respiratory mechanics state.Methods:A total of 90 patients with COPD during acute episode admitted in the Guangyuan Second People's Hospital from January 2017 to February 2018 were chosen for the study，and they were randomly divided into control group and observation group，with 45 cases in each group.The control group was treated with routine western medicine for COPD during acute episode，while the observation group was treated with Pingchuan Zhike Decoction on the basis of the treatment in the control group.Then the clinical efficacy ［totalclinical effective rate，syndrome scores of tratidional Chinese medicine(TCM）and pulmonary function parameters］ in the 2 groups were observed.The changes of respiratory mechanics state(respiratory impedance，thoracic and lung compliance）in the 2 groups were evaluated.Results:The total clinical effective rates(86.67% and 95.56%）in the observation group were higher than 64.44% and 80.00%% in the control group(P<0.05); the TCM syndrome scores and respiratory impedance in the observation group after the treatment were all lower than those in the control group(P<0.05); the thoracic and lung compliance amd the pulmonary function parameters were higher than those in the control group(P<0.05).Conclusion:The application efficacy of Pingchuan Zhike Decoction in the patients with COPD during acute episode is good，and it plays an active improvement role in the respiratory mechanics state，so its application value in the patients with COPD during acute episode.