To explore effects of acupuncture and moxibustion combined with rehabilitation on neurological function recovery and serum cytokines secretion in patients with cerebral infarction.Methods:A total of 176 cases of acute cerebral infarction patients underwent treatment in the Central Hospital of Zaokuang Group during September 2015 to February 2018 were collected as research subjects and retrospectively analyzed.According to the rehabilitative treatment plans，the patients were divided into control group(n＝90，underwent routine rehabilitation)，and observation group(n＝86，underwent acupuncture and moxibustion combined with conventional rehabilitation treatment)，taking 4 weeks as 1 course of treatment.The recovery of nerve function，serum inflammatory factors ［interleukins-6(IL-6)，interleukin-18(IL-18）and tumor necrosis factor-α(TNF-α)］ and angiogenesis indexes ［basic fibroblast growth factor(bFGF)，vascular endothelial growth factor(VEGF）and matrix metalloproteinase-9(MMP-9)］ were compared between the 2 groups after the rehabilitative treatment.Results:After 1 and 2 courses of the treatment，NIHSS score in the observation group was(16.15±2.24）and(7.37±0.91)，which were respectively lower than the control group's(22.73±2.85）and(15.09±2.21)，and the difference was statistically significant(P<0.05).After 2 courses of the treatment，the serum IL-6，IL-18 and TNF-α in the observation group were(4.18±0.52）pg/mL，(8.77±1.03）pg/mL and(9.92±1.53）pg/mL，which were respectively lower than the control group's(7.43±0.89）pg/mL，(12.01±1.55）pg/mL and(14.28±1.69）pg/mL，and the difference was statistically significant(P<0.05).the serum bFGF，VEGF and MMP-9 in the observation group were(19.77±2.84）pg/mL，(374.18±45.39）pg/mL and(54.25±7.49）ng/mL，which were respectively higher than the control group's(14.69±1.73）pg/mL，(316.21±39.74）pg/mL and(48.27±6.28）ng/mL，and the difference was statistically significant(P<0.05).Conclusion:Acupunture and moxibustion of traditional Chinese medicine on the basis of conventional rehabilitation in patients with cerebral infarction can further reduce their nerve function defects.The specific mechanism may be related to relieving patients' inflammatory response，promoting angiogenesis，etc.