Biological targeted therapies for lung cancer mainly include tyrosine kinase inhibitors，vascular growth factor receptor inhibitors，immune checkpoint inhibitors and immunological cytotherapy.Although the mechanisms of these therapies are different，side effects in clinic are mainly skin rash and diarrhea.Based on the relationship between these reactions and their corresponding curative effects as well as the theory of “dizziness response” in traditional Chinese medicine(TCM)，we suggest that the skin rash and diarrhea should be defined as “drug eruption” and “drug diarrhea”.We should make full use of the guidance value in the theory of “dizziness response” in the treatment of lung cancer using integrated traditional Chinese and western medicine，to dialectically understand and cope with the adverse reactions in biological targeted therapies，so as to enrich the connotation of “dizziness response”.