Rigorous randomized controlled trials(RCTs)are the source of unbiased evidence.Due to problems in design，implementation and outcome reports of RCTs all over the world，the value of clinical study has been decreased and investment has been wasted to a large extent.Therefore，some researchers realize that high-quality methodological research aimed at the problems in clinical study is of great significance to improve the quality of clinical study.In terms of methodological research，there are study within a trial(SWAT)and research on research(ROR)，and some organizations have been formed.Firstly，the influential SWAT programme and MIROR(Methods in Research on Research)programme，a programme that explores ROR research methods，is introduced in this study.Then their implications for the development of evidence-based Chinese medicine is discussed，so that relevant researchers may pay attention to this field.