To explore the control effect of Jianpi Yangfei Decoction on the inflammation in elderly patients with pulmonary infection.Methods:A total of 60 cases of elderly patients with pulmonary infection admitted to First Affiliated Hospital of Anhui University of Chinese Medicine from January 2016 to November 2018 were selected and divided into an observation group and a control group by random number table method,with 30 cases in each group.The control group was treated with antibiotic,and the observation group added modified Jianpi Yangfei Decoction with syndrome differentiation.The 2 groups were treated continuously for 5 days.The clinical efficacy,related clinical indicators,clinical symptoms,improvement of TCM symptoms and the serum levels of inflammatory factors before and after treatment were compared between the 2 groups.Results:After treatment,the total effective rate of the observation group was significantly higher than that of the control group(P<0.05).Compared with the control group,the symptoms remission time such as cough/expectoration,the normal time of body temperature and X-ray chest radiograph significantly advanced in the observation group(P<0.05 or P<0.01).Compared with before treatment,the scores of clinical symptoms such as cough and expectoration and the scores of TCM symptoms,and greasy and yellowish phlegm,throat snoring,strong fever and irritability significantly decreased in the 2 groups after treatment,and the observation group was significantly lower than the control group(P<0.01).Compared with before treatment,the serum levels of CRP,PCT and D-D significantly decreased in the 2 groups after treatment,and the observation group was significantly lower than the control group(P<0.05 or P<0.01); the SaO2,OI significantly increased in the 2 groups,and the observation group was significantly higher than the control group(P<0.01).Conclusion:Jianpi Yangfei Decoction can significantly improve the clinical symptoms of elderly patients with pulmonary infection,correct hypoxemia and hypercoagulability,and enhance the overall clinical efficacy.The control effect on inflammation is significantly better than western medicine alone,and it is worthy of clinical promotion.