To observe effects of Buzhong Yiqi Decoction combined with different nutritional methods on immune function in rats after hepatectomy.Methods:Forty-five rats with successfully duplicated cirrhotic hepatoma and successful hepatectomy by Higgins method were included in the study.They were randomly divided into routine group，integrated Chinese and western group A and integrated Chinese and western group B，with 15 rats in each group.The routine group received oral feeding，the integrated Chinese and western group A was used Buzhong Yiqi Decoction+ parenteral nutrition，and the integrated Chinese and western group B was treated with Buzhong Yiqi Decoction+ enteral nutrition.They were intervened continuously for 10 d.Expression differences of nutritional indexes［hemoglobin(Hb)，total cholesterol(TC)，triglyceride(TG)and low density lipoprotein(LDL)］and immune indexes(CD3+，CD4+，CD8+，IgG，IgM and IgA)were compared among the groups.Results:1)The levels of Hb，TC，TG and LDL in the 3 groups were lower than the normal values.Among the 3 groups，those in the integrated Chinese and western groups were higher than those in the routine group，and those in the integrated Chinese and western group B were higher than those in the group A(P<0.05).2)There was no significant difference in the CD3+，CD4+，CD4+/CD8+，IgG，IgM，IgA，IL-4，IL-6 and TNF-α among the 3 groups before the treatment(P>0.05).After the intervention，the above indicators in the 3 groups were significantly lower than those before the treatment(P<0.05).Those in the integrated Chinese and western groups were lower than those in the routine group，and those in the integrated Chinese and western group B were higher than those in the group A(P<0.05).After the intervention，the CD8+ in the 3 groups was increased significantly compared with that before the treatment(P<0.05).That in the integrated Chinese and western groups was lower than that in the routine group，and that in the integrated Chinese and western group B was lower than that in the group A(P<0.05).Conclusion:Buzhong Yiqi Decoction combined with enteral nutrition can improve nutritional status and immune function of cirrhotic hepatoma patients after operation.