To explore the effects of integrated traditional Chinese and western medicine on the vision recovery and serum trace elements of patients with Herpes Simplex Keratitis(HSK).Methods:A total of 86 cases of patients with HSK in Inner Mongolia Baogang Hospital from January 2015 to October 2016 were selected and divided randomly into an observation group(n＝43)and a control group(n＝43)according to random number table.The control group was treated with ganciclovir eye drops and chondroitin sulfate eye drops，and observation group was treated with Qinggan Mingmu Decoction on the basis of control group.2 groups were treated for 4 weeks continuously.The clinical efficacy of 2 groups was compared.The recovery of vision，serum trace elements and tear immune factor level of 2 groups before and after treatment were compared.Results:After treatment，the total effective rate of the observation group was significantly higher than that of the control group(P<0.05); After treatment，the visual analogue score and visual acuity of patients in the observation group were remarkedly higher than those before treatment(P<0.01)and control group(P<0.05); After treatment，the serum levels of Fe，Ca and Cu in the observation group were significantly lower than those in the control group and before treatment(P<0.01); Serum zinc level was significantly higher than that before treatment and control group(P<0.01); After treatment，the levels of IgA，IgG and C3 in tear of patients in the observation group were prominently higher than those before treatment and control group(P<0.01).Conclusion:Integrated traditional Chinese and western medicine in the treatment of HSK can promote effectively the recovery of vision of patients，enhance the body anti-virus ability，and the clinical efficacy is better than the treatment with western medicine alone.