To observe the clinical effects of three needles of shoulder combined with rehabilitation training on shoulder-hand syndrome and to explore its clinical value in order to enrich the treatment of shoulder-hand syndrome.Methods:From January 2016 to December 2017，82 patients with acute shoulder-hand syndrome in the Fourth Hospital of Huangshi City were selected as the research object.According to the order of visiting，they were divided into a control group and an observation group，with 41 cases in each group.Patients in both groups were given rehabilitation training such as neuronutrition，individualized glucose control and lipid lowering therapy，exercise therapy and occupational therapy.In the observation group，on the basis of this，shoulder three schemes can effectively improve the rehabilitation quality of patients with acute shoulder-hand syndrome，improve the efficiency of clinical symptoms，enhance the clinical efficacy，and acupuncture as the main acupoint.Acupuncture at symptomatic points was given once a day for 6 days a week.2 groups of patients were treated for 8 weeks for a course of treatment.Visual analogue score(VAS)，upper extremity action research scale(ARAT)，upper extremity joint activity Fugl-Meyer score(FMA)，Chinese clinical neurological deficit score(CSS)score and serum inflammatory factors were observed before and after treatment，and were compared before and after treatment and between groups.The symptoms of shoulder pain，limited movement，wrist swelling，fever and pain，and limited flexion of fingers were evaluated，and the improvement time of the above symptoms was counted.After completion of treatment，the clinical efficacy of the 2 groups was evaluated and compared.Results:1)After 8 weeks of treatment，the VAS score and CSS score of shoulder pain in both groups were significantly decreased than those before treatment，and the observation group was lower than the control group(P<0.05).2)After treatment，the serum inflammatory factors IL-2，IL-6 and TNF-α in the 2 groups were significantly decreased than before treatment，and the observation group was lower than the control group(P<0.05).3)After treatment，the ARAT score and FMA score of the 2 groups were increased than those before treatment，and the observation group was higher than the control group(P<0.05).4)The clinical symptoms of shoulder pain, limited movement, redness and swelling of wrist and limited finger flexion were significantly shorter in the observation group(P<0.05).5)After the completion of treatment，the total effective rate of the observation group was significantly higher than that of the control group(P<0.05).Conclusion:Shoulder three needles combined with rehabilitation training can improve the inflammation of patients，promote the improvement of clinical symptoms，improve the data effect，and has high clinical value.