Novel coronavirus pneumonia(NCP)is a disease of highly epidemic and infectious.The main clinical manifestations of NCP are fever,dry cough and fatigue.Severe cases can have dyspnea,and critical cases rapidly progress to respiratory distress syndrome,septic shock,and even death.Based on the relevant clinical reports and the first-line data,combined with the theory of TCM Febrile Disease,it is considered that NCP belongs to the category of “Plague” in TCM,and the pathogenesis is characterized by the intertwist of cold with heat,root deficiency and branch excess.The main pathogenic factors are “Cold”,“Heat” and “Dampness”,mainly located in “Lung” and “Liver”,involving “Spleen” and “Kidney”.Its transmission speed is fast,and its clinical manifestations are as follows: the liver and kidney are deficient due to the injury of Yin and Yang,the lung heat and spleen cold,the wood fire punishes the gold,and the cold and heat are intertwisted.According to the characteristics of the pathogenesis of NCP,this paper proposed different stages of TCM treatment plan and medication strategy.At the same time,this paper analyzes the feasibility of Mahuang Shengma decoction as the main prescription in the treatment of NCP.We believe that Mahuang Shengma decoction has the functions of clearing upper jiao and warming the lower jiao,simultaneous treatment of exterior and interior,while the treatment refers to the lung,spleen,liver and kidney.In a word,it has the functions of warming,clearing,promoting and tonifying.It conforms to the characteristics of TCM Syndromes of NCP and provides reference for clinical prevention and treatment of epidemic situation.