Abstract:The suitable distribution regions of Fritillaria unibracteata, one of the famous Daodi-herbs produced in Sichuan Province was studied by remote sensing and GIS spatial analysis of the suitable environmental indicators of Fritillaria unibracteata. The results showed that the suitable regions of Fritillaria unibracteata were Hongyuan, Songpan, Ruoergai, Jiuzhaigou, Maoxian, Pingwu, Heishui, Lixian and Maerkang, etc. Hongyuan, Songpan, Ruoergai, Jiuzhaigou, Maoxian, Heishui and Maerkang were the best suitable regions of Fritillaria unibracteata, accounting for 45.2% of the total suitable areas. It was learned from the field investigation of Fritillaria unibracteata that our results coincided with the wild investigation of Fritillaria unibracteata in Sichuan. Remote sensing and GIS technology is a suitable tool for investigation of Fritillaria unibracteata. Our results also provide support for rational planting and monitoring control of other wild herbs.