Dampness toxin and wind are the main pathological factor of novel coronavious pneumonica(NCP)，its generation and spread also have significant natural and physical characteristics. Under the combined action of multiple incentives，the etiology of dampness toxin complicated by wind has the characteristics of rapid spread，intense toxicity，lingering illness，and easy transmission. It is closely related to the occurrence of inflammatory storm that induce the conversion of light and ordinary patients to severe and critically severe ones. The paper studied the relevant literature and case reports of NCP，and analyzed the natural and physical factors of the outbreak of NCP from the perspective of “harmony between man and nature”. The pathological changes of inflammatory storm during the evolution of NCP was discussed from the perspective of dampness toxin complicated by wind's pathological properties and transmission laws. The mainly treatment principle for NCP was proposed which is clearing heat and purging lung，removing toxicity and dispelling filth，invigorating spleen for eliminating dampness，dispelling wind and dredging collateral.