Based on the data analysis software Excel and SPSS 15.0，the rules of prescriptions of Chinese medicine for preventing Novel Coronavirus Pneumonia(NCP) in various regions were analyzed，the characteristics and thoughts of medication were summarized，so as to provide reference for NCP prevention.Methods:Diagnosis and treatment plans of National，provincial，municipal and autonomous regions' Health Commission and Administration of Traditional Chinese Medicine from webpage and Chinese database before February 5，2020 were retrieved.Results:A total of 52 prophylaxis for different populations (including children，the elderly，pregnant women，etc.) from 17 provinces and cities were included in this study.A total of 79 Chinese medicines were involved and 19 high-frequency drugs were obtained.Four core drugs were found; 3 types of drug combinations were obtained by cluster analysis.Conclusion:The core TCM medicines for preventing NCP are milkvetch root，largehead atractylodes rhizome，divaricate saposhnikovia root and liquorice root.Benefiting Qi and strengthening spleen，clearing heat and eliminating dampness，regulating Qi flow should be emphasized in prophylaxis.Syndrome differentiation should be applied in the prevention.