基于数据挖掘的中药外治腹泻特点分析
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河南省产学研项目(182107000029);国家国际合作基地(2016-65)


Characteristic Analysis on External Treatment of Chinese Materia Medica in Diarrhea Based on Data Mining
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    摘要:

    目的:探究以中药外治方法治疗腹泻的临床用药特点。方法:搜索中国知网中临床研究文献,归纳文献中的用药疗程、用药时间、用药频率、剂型、赋形剂、用药剂量、给药方式,总结中药临床外治腹泻的用药特点与规律、不良反应。将临床文献中含有腹泻外治的中药处方录入Excel表,建立数据库,并应用Clementine12.0、Excel统计软件进行数据分析。结果:腹泻临床外治中药一般为吴茱萸、丁香、肉桂、白术、黄连等;以温里药、补虚药、清热药为主;常用药对为肉桂-丁香、吴茱萸-丁香等。给药方式主要有外敷法、灌肠法;给药频率主要为1~3次/d;用药时间多为在0≤t≤1 h、6 h<t≤12 h内;用药疗程多在1个月内,主要在1~7 d;赋形剂主要有醋、酒、水。结论:对调查结果进行统计与分析,为中药外用技术的规范化提供理论支撑,提高腹泻外治临床疗效。

    Abstract:

    To explore clinical medication characteristics of Chinese materia medica to treat diarrhea externally.Methods:Clinical research literature in CNKI was retrieved.The course of medication,medication time,frequency of medication,dosage form,excipient,dosage and administration methods in the literature were concluded.Clinical medication characteristics and rules,as well as adverse reactions in treating diarrhea externally by Chinese materia medica were summarized.Prescriptions of Chinese materia medica for external treatment of diarrhea in the clinical literature were recorded into Excel,and a database was established.Clementine 12.0 and Excel statistical software were used for data analysis.Results:Medicines in the clinically external treatment of diarrhea were Fructus Evodiae,Flos Caryophylli,Cortex Cinnamomi,Rhizoma Atractylodis Macrocephalae,Rhizoma Coptidis,etc.It was mainly composed of interior-warming medicines,deficiency-tonifying medicines and heat-clearing medicines.Commonly used medicine pairs were Cortex Cinnamomi-Flos Caryophylli,Fructus Evodiae-Flos Caryophylli,and so on.The administration methods included external application and enema.The frequency of medication ranged mainly 1 time/d-3 times /d.The medication time was mostly 0 ≤ n ≤ 1 h and 6 h < n ≤ 12 h.The course of medication was usually within 1 month,mainly 1-7 d.The excipients were mainly vinegar,wine and water.Conclusion:The results of the survey were statistically analyzed to provide theoretical support for standardization of the external use of Chinese materia medica,and improve clinical efficacy of external treatment in diarrhea.

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雷会霞,白明,苗明三.基于数据挖掘的中药外治腹泻特点分析[J].世界中医药,2020,(03).

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  • 收稿日期:2020-01-10
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  • 在线发布日期: 2020-03-16
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