To evaluate the effects of Xufu Zhuyu Capsule on inflammatory factors, angiogenesis and endothelial function in patients with coronary heart disease angina (CHDA) using xuefuzhuyu capsule.Methods:A total of 76 CHDA patients hospitalized in the department of cardiology of Zibo Traditional Chinese Medicine Hospital from March 2017 to March 2018 were randomly divided into the a research group and a control group, with 38 patients in each control group.The control group were treated with conventional therapy only, and the research group were treated with Xuefu Zhuyu Capsule on the basis of the control group.The levels of the inflammatory factors (TNF-and hs-CRP), proangiogenic factor (VEGF and bFGF) and vascular endothelial function (NO, ET-1 and TXB2) and total effective rate were compared between 2 groups.Results:The total effective rates were 78.94% in the research group, and 57.89% in the control group, with significant difference (P<0.05).After treatment, the levels of VEGF, bFGF and NO were increased (P<0.05) and the increase was more significant in the research group than in the control group and the difference is statistically significant (P<0.05).Conclusion:Xuefu Zhuyu Capsule can reduce inflammation reactions, promote vascular endothelial repair and angiogenesis, increase blood oxygen supply to myocardium, and improve myocardial injury.It has a very significant clinical effects in patients with CHDA and can be widely used.