醒脑开窍针刺法治疗血管性痴呆患者的疗效
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湖南省自然科学基金项目(2019JJ8002680026)


Effects in Patients with Vascular Dementia Using Acupuncture Method of Inducing Resuscitation
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    摘要:

    目的:探究醒脑开窍针刺法对血管性痴呆(VD)患者的简易智能状态量表(MMSE)评分、Barthel指数及基质金属蛋白酶(MMP)的影响。方法:选取2017年1月至2018年1月湖南省脑科医院收治的血管性痴呆患者共110例作为研究对象,随机分为观察组和对照组,每组55例。对照组采用常规针刺疗法;观察组采用醒脑开窍针刺疗法,2组疗程均为4周。比较2组患者治疗后治疗有效率及治疗前后MMSE、Barthel指数及MMP水平。结果:观察组、对照组的治疗有效率分别为92.72%和78.18%,差异有统计学意义(P<0.05);治疗后2组患者MMSE和Barthel指数均显著升高,差异有统计学意义(P<0.05),且观察组高于对照组,差异有统计学意义(P<0.05);治疗后2组患者的MMP-2和MMP-9值均下降,差异有统计学意义(P<0.05),且观察者组患者的MMP-2和MMP-9低于对照组,差异有统计学意义(P<0.05)。结论:醒脑开窍针刺法对VD患者疗效显著,能够有效缓解痴呆症状。

    Abstract:

    To explore the effects on MMSE scores, Barthel indexes and matrix metalloproteinase (MMP) in patients with vascular dementia (VD) by using acupuncture method of inducing resuscitation.Methods:A total of 110 patients with VD in Hunan Brain Hospital were randomly divided into an observation group (55 cases) and a control group (55 cases).The control group was treated with routine acupuncture method while the observation group was treated with acupuncture method of inducing resuscitation.There were 2 weeks of treatment for the 2 groups.The total effective rates, MMSE scores, Barthel indexes and levels of MMP were compared between the 2 groups.Results:The total effective rates in the observation group and the control group were 92.72 % and 78.18 %, respectively, with significant difference (P<0.05).After treatment, the MMSE scores and Barthel indexes in the 2 groups increased significantly (P<0.05), and those in the observation group were higher than those in the control group, with significant difference (P<0.05).After treatment, the levels of MMP-2 and MMP-9 in the 2 groups decreased significantly (P<0.05); Moreover, those in the observation group were lower than those in the control group, with significant difference (P<0.05).Conclusion:Acupuncture method of inducing resuscitation is an effective therapy in treating VD patients and can effectively relieve the symptoms of dementia, which is worthy for further promotion and application.

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叶海森,武凯歌,张湘斌,陈曦,周霞峰,曹慧.醒脑开窍针刺法治疗血管性痴呆患者的疗效[J].世界中医药,2020,(07).

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  • 收稿日期:2020-02-06
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  • 在线发布日期: 2020-04-27
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