To observe the improvement of symptoms,quality of life and satisfaction of patients with functional constipation of different ages,and to evaluate the safety of Shouhui Tongbian Capsule.Methods:A total of 2 396 patients with functional constipation were divided into 3 groups:18～40 years old,41～60 years old and over 61 years old.The main index of this study was to observe the therapeutic effect of Shouhui Tongbian Capsule after 14 days,the change of Wexner score of intestinal function before and after treatment and the evaluation of safety.The secondary index of this study was to record the impact of Shouhui Tongbian Capsule on the quality of life of patients,and to observe the long-term efficacy and safety of Shouhui Tongbian Capsule 1 month,2 months and 3 months after taking.Results:Shouhui Tongbian Capsule could improve the defecation frequency,difficulty degree and defecation time.The results showed that the improvement effect of 14 days after taking the capsule was better than 7 days(P<0.001).The comparison between groups showed that the younger patients had better improvement effect than the older patients(P<0.001).Similarly,Shouhui Tongbian Capsule can improve the quality of life and satisfaction of patients.The long-term improvement effect was better than the short-term improvement effect(P<0.001).The comparison between groups showed that the younger patients had better improvement effect than the older patients(P<0.001).Conclusion:The results of this study provide a strong basis for the reevaluation of the efficacy and safety of Shouhui Tongbian Capsule after it is put on the market.