Biomarkers are particularly important indicators for judging the damage and state of organs.Their establishment is a chemical or physical change derived from physiological and functional changes.Drug-induced renal injury is common in clinics.Kidney injury is usually very secretive and not easy to find in the early stage.Therefore,renal injury markers are essential for evaluating the significance of kidney structure and function.This paper intends to classify the structure of kidney and function of the drugs,and summarize the existing markers for evaluating kidney damage,in order to make an evaluation basis for the use of drugs in the evaluation of kidney damage.