From modern medical research perspective,the modern research progress of Radix Aconiti Lateralis Preparata compatible prescription is reviewed to clarify the pharmacological action and mechanism of various prescription,and to lay a theoretical foundation for the concept of multi-target cooperative medicine.The domestic and foreign literature related were searched,and the research status of various prescription was reviewed from the aspects of compatibility,pharmacological action and mechanism of Chinese medicine.It was found that Radix Aconiti Lateralis Preparata was often compatible with Radix Ginseng Rubra,Radix Glycyrrhizae,Herba Ephedrae,Radix et Rhizoma Rhei and other traditional Chinese medicines,and its prescription had the pharmacological effect of enhancing effect and reducing toxicity,but the multi-target regulation network of active ingredients in the prescription in vivo needs to be further systematically explored.The compatibility mode and therapeutic effect of Radix Aconiti Lateralis Preparata compatible prescription provide a new idea for the multi-target cooperative treatment strategies.