Prescription is the final embodiment of traditional Chinese medicine(TCM)clinical diagnosis and treatment process.This paper analyzes the prescription law of Professor DING Zhiguo in the treatment of chronic lymphocytic thyroiditis with the aid of TCM inheritance system.Methods:By sorting out the prescriptions of traditional Chinese medicine for the treatment of simple chronic lymphocytic thyroiditis from 2017 to the present as a data source，109 new prescriptions for the treatment of chronic lymphocytic thyroiditis that meet the requirements were screened out，and a database was established.Frequency statistics and correlation were used for data mining.The core drugs and their meridian，nature and flavor，and prescription rules were analyzed and studied.Results:A total of 84 Chinese medicines were involved in the prescription.The number of prescription drugs with a frequency of ≥75 times received 13 drugs，6 core combinations and 3 new prescriptionsere were evolved; the core drugs mainly belonged to the lung and spleen channels，and their nature and flavor were bitter and sweet.Conclusion:The drug law of Professor DING Zhiguo in the treatment of CLT were explored and summarized，opening up new ideas for the treatment of CLT with TCM，and to provide a new scheme for the treatment of Hashimoto patients.