To systematically assess the effectiveness and safety of aerosol inhalation of Chuankezhi Injection for the treatment of bronchial asthma.Methods:Databases including Embase，Cochrane Library，SinoMed，CNKI and Wanfang Data were electronically searched in April 2019 for randomized controlled trials( RCTs) on Chuankezhi Injection for the treatment of bronchial asthma.According to the inclusion and exclusion criteria，2 authors independently conducted literature screening and data extraction，and assessed the risk of bias of included studies.Then，meta-analysis was performed by RevMan 5.3 software.Results:A total of 9 RCTs were included with a total of 842 patients.Among them，there were 421 cases in the test group and 421 cases in the control group.Meta-analysis results showed：1) In terms of effectiveness，the total effective rate of Chuankezhi Injection aerosol inhalation combined with conventional treatment for bronchial asthma intervention (RR=1.22，95% CI [1.15，1.29]，P<0.000 01).The actual value of lung function FEV1 accounted for the percentage improvement of the predicted value (MD=6.03，95% CI [4.23，7.84]，P<0.000 01).The actual basic test value of FEV1 (MD = 0.44，95% CI [0.32，0.56]，P<0.000 01).The actual PEF value of lung function as a percentage of the predicted value (MD = 6.03，95% CI [4.23，7.84]，P<0.000 01)，the actual basic test value of FEV1 (MD = 0.58，95% CI [0.36，0.80]，P<0.000 01) is better than conventional treatment alone; 2) in terms of safety，the incidence of adverse reactions of Chuankezhi Injection combined with conventional treatment for bronchial asthma is not statistically significant compared with conventional treatment (RR=0.59，95% CI [0.26，1.35]，P=0.21).Conclusion:Based on the existing clinical evidence，the effect of aerosol inhalation of Chuankezhi Injection combined with conventional treatment for bronchial asthma is better than conventional treatment alone.However，because the methodological quality of the included studies is generally low，follow-up clinical studies also require strict methodological design and quality control in order to provide higher-quality evidence.