The Systematic and holistic view of traditional Chinese medicine(TCM)is the basic world view of TCM theory.Metabolic syndrome(MetS)is a complex and multi-factor clinical syndromes that seriously endanger the human body's health and collectively emerge.At present，Western medicine clinical treatment is mostly aimed at a single factor intervention，rather than multi-target intervention measures.In this paper，it is discussed that the application of the holistic view of TCM in the etiology，pathogenesis，syndrome differentiation and treatment of metabolic syndrome to provide new treatment ideas for the treatment of metabolic syndrome.