Immune thrombocytopenia (ITP) is an autoimmune disease characterized by thrombocytopenia,and its pathogenesis and causes have not been completely clarified.ITP's TCM disease is called “purpura”.Professor CHEN Xinyi's team thinks that the pathogenesis of ITP is “spleen deficiency and spleen not controlling blood”,so Jianpi Yiqi Shexue Formula has achieved good clinical effect.For this reason,a series of clinical and basic studies have been carried out to confirm its immunomodulatory effect,so as to clarify its specific mechanism.In this paper,Professor CHEN Xinyi summarized and discussed the immune indexes adopted by Jianpi Yiqi Shexue Formula in treating ITP research during the clinical trial of the National Key Basic Research Development Program (“973” Program).