Lichen sclerosus of vulva is a difficult gynecologic disease characterized by severe vulvar itching.The incidence rate has gradually increased in recent years,and relapsed easily,there is no cure method at present.Professor WANG Xiuxia is a doctoral supervisor of Heilongjiang University of Traditional Chinese Medicine and guidance teachers for academic experience inheritance of the third and fourth groups of TCM experts in China.She has been engaged in gynecology teaching,scientific research and clinical work for more than 50 years and she is good at diagnosis and treatment of gynecological complications,especially for vulvar lichen sclerosus.She had unique insights of it.Adhering to the principle of seeking the root of the disease and giving consideration to both the whole and the part,Professor WANG thinks this disease should be treated from 2 aspects deficiency and excess.She put forward the idea of internal treatment to nourish the liver and kidney,clearing away heat and removing dampness,dispelling wind and relieving itching,and made leukoplakia 1,leukoplakia 2 formula by herself for vulva hip bath,combined with local closure of placental polypeptide,interferon for external use,red light irradiation and other integrated traditional Chinese and Western Medicine,and the clinical effect is remarkable.Professor WANG Xiuxia's experience in the diagnosis and treatment of vulvar lichen sclerosis was deeply analyzed from the aspects of etiology and pathogenesis,differentiation of symptoms and signs,medication characteristics and typical cases in this paper,so as to provide more references for the treatment of such patients.