加味小建中汤对胃肠道功能紊乱患者的临床研究
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湖北省卫计委和计划生育委员会科研项目(WJ2015MB232)


Effect of Modified Xiaojianzhong Decoction on Patients with Gastrointestinal Dysfunction
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    摘要:

    目的:观察研究加味小建中汤对胃肠道功能紊乱患者肠道菌群及胃肠激素水平的影响。方法:回顾分析2016年1月至2018年10月湖北医药学院附属医院收治的慢性心力衰竭合并胃肠道功能紊乱患者60例作为研究对象,根据治疗方法不同分为对照组(n=16)和观察组(n=44),对照组采用常规西医治疗,观察组采用加味小建中汤和常规西医治疗,比较观察2组患者治疗后的肠胃动力改善,症状改善以及肠道菌群,胃肠激素水平改善的情况。结果:使用了加味小建中汤治疗的观察组患者经过治疗以后临床疗效,肠胃动力改善,病症改善以及肠道菌群,胃肠激素水平改善的情况均较对照组更具优势,差异均有统计学意义(P<0.05)。结论:加味小建中汤对于心力衰竭合并胃肠道功能紊乱的临床治疗效果显著,对于患者胃肠道功能的恢复具有显著的促进作用,且能够有效的减轻其病症,改善患者的胃肠激素水平以及患者的肠道菌群水平。

    Abstract:

    To observe the effect of modified Xiaojianzhong Decoction on intestinal flora and gastrointestinal hormone levels in patients with gastrointestinal dysfunction.Methods:From January 2016 to October 2018,a total of 60 patients with chronic heart failure complicated with gastrointestinal dysfunction admitted to Affiliated Hospital of Hubei Medical College were selected as the research objects and were divided into a control group (n=16) and an observation group (n=44).The control group was treated with conventional Western medicine,and the observation group was treated with modified Xiaojianzhong Decoction and conventional Western medicine.The improvement of gastrointestinal motility,symptom improvement,intestinal flora and gastrointestinal hormone levels were compared between the 2 groups.Results:In the observation group,the patients who were treated with modified Xiaojianzhong Decoction had more advantages than the control group in clinical effect,improving gastrointestinal motility,symptoms,intestinal flora and gastrointestinal hormone levels.The difference was statistically significant (P<0.05).Conclusion:For the clinical treatment of heart failure complicated with gastrointestinal dysfunction,modified Xiaojianzhong Decoction has a significant effect.It has a significant effect on promoting the recovery of gastrointestinal function of patients,and can effectively alleviate the symptoms of the disease,improve gastrointestinal hormone levels and intestinal flora levels for the patients.

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刘伟,刘莹莹,高学清,汪雪晴,柯娟.加味小建中汤对胃肠道功能紊乱患者的临床研究[J].世界中医药,2021,(04).

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  • 收稿日期:2019-11-06
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  • 在线发布日期: 2021-04-16
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