Baihu plus Renshen Decoction is the main prescription for clearing heat,invigorating qi and invigorating fluid.Starting with using Baihu plus Renshen Decoction as the main treatment and the pathogenesis of diabetes,this paper discusses the characteristics of Baihu plus Renshen Decoction in the treatment of diabetes,and explains the possible mechanism of Baihu plus Renshen Decoction in the treatment of diabetes through the study of compatibility,modern pharmacological studies of modern physicians,and its disassembled prescriptions.And through the precautions of use to guide the clinic,it is hopeful to strengthen the understanding of Baihu plus Renshen Decoction and provide reference for the treatment of diabetes.