To evaluate Boai Capsule on rat blood pressure effects of spontaneously hypertensive model，type of spontaneously hypertensive stroke model，and renal artery stenosis hypertensive model.Methods:Rats were randomly assigned into a wky group or sham-operation group，a model control group，a captopril positive medicine control group (5.4 mg/kg)，a large dose，a medium dose and a low dose of Boai Capsule group (6.42 g/kg，3.24 g/kg，1.62 g/kg).Before and after dosing Bo-Ai Capsule，the rat tail artery blood pressure was measured by using automatic blood pressure recorder.Results:The large，medium，and low dose groups (6.42 g/kg，3.24 g/kg，1.62 g/kg) of Boai Capsule can reduce the blood pressure value of SHR model rats to varying degrees.Compared with the model control group，after 2 weeks of administration，the blood pressure value of each administration group decreased，and the difference was statistically significant (P<0.01).The blood pressure value still decreased to varying degrees after stopping the drug for 4 weeks，and the difference was statistically significant (P<0.01).The large and medium dose administration group of Boai Capsule (6.42 g/kg，3.24 g/kg) can reduce the blood pressure value of SHRsp model rats to different degrees.Compared with the model control group，the blood pressure value was significantly reduced after 1 week of administration，and the difference was statistically significant (P<0.01).The blood pressure value of the large dose of Boai Capsule group (6.42 g/kg) was still significantly reduced after 4 weeks of discontinuation，and the difference was statistically significant compared with the model control group (P<0.01).Compared with model group，the blood pressure of renal artery stenosis hypertensive model rats decreased significantly in large，medium and low dose groups (6.42 g/kg、3.24 g/kg，1.62 g/kg) of Boai Capsule after dosing one week and the difference was statistically significant (P<0.01).Conclusion:Boai Capsule had effects of decreasing blood pressure of spontaneously hypertensive and renal artery stenosis hypertensive models.